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Biochemistry and Biotechnology

Course Code
BCBT 100  Credits
Title The Science of Cooking 
Lasc Area Goal 3 Lab  
Course Outline Course Outline 
Description This course will look at cooking from a scientific perspective to understand the food we eat and enjoy. Cooking may be the oldest and most widespread application of science. Students will use principles of biochemistry with some chemistry and biology to analyze food and investigate how cooking works. Students will also do several edible experiments and look at the science behind how it all works. Each week a different food will be explored. Topics include, but are not limited to, what makes a good experiment, death by chocolate, cheese making, the joys of hot sauce and salsa food biochemistry, the science of spice, and what is taste? This course includes a lab component. Students are expected to conduct three food experiments independent of class time. Learn to be a better cook by understanding food at the molecular level. MnTC Goal 3. 



Course Code
BCBT 120  Credits
Title Introduction to Biochemistry & Biotechnology Careers 
Course Offering Fall On Demand  
Course Offering Spring Every Year  
Course Outline Course Outline 
Description Introduction to biochemistry and biotechnology careers. Topics may include: current and future career options & trends; training and background needed for these careers; scope of industry; job types at different levels of training. Primer to BCBT graduate, professional, and industry careers. 



Course Code
BCBT 200  Credits
Title Introduction to the Biochemistry and Biotechnology Industry 
Course Outline Course Outline 
Description This course is an introduction to the biochemistry and biotechnology industry including an overview of the different industry sectors. Topics covered include the scientific advances and economic impact of the biochemistry and biotechnology industry as well as the training requirements for entering the industry's workforce. Prerequisite: One semester of Biosciences or Chemistry with lab. 



Course Code
BCBT 210  Credits
Title Introduction to Vaccinology Seminar 
Course Outline Course Outline 
Description This course will introduce students to the field of vaccinology and aspects of the bioscience industry related to vaccine discovery, production, and testing. Students will learn about the history of vaccines; the production of vaccines in a regulated environment; the benefits and concerns with vaccine use. This course is required for the Vaccinology Minor. Students should have one year of Biology or one year of Chemistry courses. 



Course Code
BCBT 220  Credits
Title Survey of BCBT Research and Methodology 
Course Offering Fall Every Year  
Course Offering Spring On Demand  
Course Outline Course Outline 
Description Introduction to research approaches in areas of biochemistry and biotechnology research. Seminar topics include: application of the scientific method in BCBT research fields; breadth and depth of background/training to be successful in research; reading scientific literature; introduction to ethics in research. Seminars will relate to current research by MSUM affiliated faculty that students may work with later in their program. 



Course Code
BCBT 290  Credits
Title Topics in Biochemistry & Biotechnology 
Course Outline Course Outline 
Description Exploration of a specific Biochemistry / Biotechnology topic. This course may be repeated as topic varies. 



Course Code
BCBT 360  Credits
Title Team-Based BCBT Research 
Prerequisite CHEM 400 CHEM 405 BIOL 385 BIOL 385L  
Course Offering Spring Every Year  
Course Outline Course Outline 
Description Students will participate in a team-based research experience in a principle investigator system in which they will apply advanced research techniques to a current research problem. In addition to research skills, as part of a research team the students will learn research management, team coordination, and conflict resolution skills. 



Course Code
BCBT 397  Credits 1-3 
Title Biochemistry & Biotechnology Research 
Course Offering Fall Every Year  
Course Offering Spring Every Year  
Course Offering Summer On Demand  
Course Outline Course Outline 
Description Faculty-mentored independent research in Biochemistry and Biotechnology. Course may be repeated for credit. 



Course Code
BCBT 410  Credits
Title Vaccinology Senior Seminar 
Prerequisite BCBT 210 
Course Outline Course Outline 
Description This course will cover the vaccine types, delivery, efficacy, and safety. Students will learn about the mechanism of action of different vaccines; traditional verses modern vaccine production methods, the process of clinical trials and approval for new vaccines; and discuss ethical concerns related to vaccine use. The course is required for the Vaccinology Minor. 



Course Code
BCBT 420  Credits
Title Intro to Working in a Regulated Biochemistry and Biotechnology Industry 
Prerequisite BCBT 200 
Course Outline Course Outline 
Description This course will cover the basic structure of the regulated workplace; introduction to regulatory affairs, introduction to regulatory language: FDA and USDA; an overview of good practices: good laboratory practices (GLP), good manufacturing practices (GMP) and good clinical practices (GCP); introduction to quality systems: quality control, quality assurance, ISO9000, and six sigma; introduction to validation. Student must be in junior standing in a bioscience or chemistry major. 



Course Code
BCBT 425  Credits
Title Introduction to Validation in the Biochemistry and Biotechnology Industry 
Prerequisite BCBT 200 
Course Outline Course Outline 
Description This course provides an overview of validation in the biochemistry and biotechnology industry including biopharma, biomanufacturing, and basic and clinical research. Topics will include: 1) The science of validation; 2) Qualification, calibration, and certification of equipment; 3) Validation of biological assays; 4) Creation and Application of Validation Programs. Student must be in junior standing in a bioscience or chemistry major. 



Course Code
BCBT 430  Credits
Title Intro to Quality Assurance and Quality Control in Biochem Biotech Industry 
Prerequisite BCBT 200 
Course Outline Course Outline 
Description This course covers the origins, history of quality and the major concepts, theories, principles and founders; quality planning, assurance and improvement; the roles and responsibilities of quality assurance and quality control. Student must be in junior standing in a bioscience or chemistry major. 



Course Code
BCBT 435  Credits
Title Ethics in the Biochemistry and Biotechnology Industry 
Prerequisite BCBT 200 
Course Outline Course Outline 
Description This course will cover ethical issues in the Biochemistry and Biotechnology Industry ranging from legal requirements for notebooks, issues with data falsification and misrepresentation, and issues of genetic manipulation and cloning among others. Student must be in junior standing in a bioscience or chemistry major. 



Course Code
BCBT 450  Credits
Title Molecular and Biophysical Chemistry 
Prerequisite CHEM 400 MATH 261 
Course Outline Course Outline 
Description Biophysical study of molecular structures, biophysical techniques, and biological mechanisms. Includes the biological functions of cells, tissues and organisms in terms of the structure and behavior of biological molecules and techniques. 



Course Code
BCBT 460  Credits
Title BCBT Literature Review and Presentation 
Prerequisite BCBT 360 
Course Offering Spring Every Year  
Course Outline Course Outline 
Writing Intensive Yes  
Description Advanced analysis and critique of primary publications in biochemistry and biotechnology in a journal club format. Topical discussions and written reviews will facilitate a deeper understanding of advanced research methods and the publication process. 



Course Code
BCBT 461  Credits
Title Biotechniques: Nucleic Acids & Bioinformatics 
Prerequisite BIOL 385 BIOL 385L 
Lasc Area No Goal  
Course Offering Fall Every Year  
Course Outline Course Outline 
Description Advanced theory and practice of techniques for working with DNA and RNA for research and applications. Development of modern bioinformatics skills and applications to genomic research.  



Course Code
BCBT 462  Credits
Title Cell Culture and Immunochemistry 
Prerequisite BIOL 111 CHEM 360 
Course Offering Fall On Demand  
Course Offering Spring On Demand  
Course Outline Course Outline 
Description An introduction to animal cell culture and immunochemical staining techniques. Students will learn the basic theory of cell culture and the use of antibodies and epitope tagged proteins to evaluated cellular functions. Students will work with mammalian cell cultures, transfect cells, insert epitope tagged proteins as functional markers in cells, apply antibody staining techniques, culture and learn techniques involved in maintaining and manipulating cell cultures. 



Course Code
BCBT 463  Credits
Title Proteomics and Advanced Chromatography 
Prerequisite CHEM 410 and CHEM 405 
Course Offering Fall On Demand  
Course Offering Spring On Demand  
Course Outline Course Outline 
Writing Intensive No  
Description Introduction to proteomics, recombinant protein expression and purification using advanced chromatography systems. Students will study these topics and practice in the lab. Students will express recombinant fusion proteins in different systems and purify these proteins using FPLC or HPLC. Students will also study advanced proteomics techniques including 2D electrophoresis, mass spectrometry and protein bioinformatics. This is a lab/lecture course where students will study background and theory and practice some of these techniques in the lab. 



Course Code
BCBT 463  Credits
Title Proteomics and Advanced Chromatography 
Prerequisite CHEM 410 and CHEM 405 
Course Offering Fall On Demand  
Course Offering Spring On Demand  
Course Outline Course Outline 
Description An introduction to proteomics, mass spectrometry, and advanced chromatography systems. Students will learn the theory and development of proteomics as a key component of systems biology and explore how proteomic techniques can be applied to gain insight into a wide variety of biochemical and biotechnological research problems. Advanced techniques include 2D electrophoresis, liquid chromatography, quantitative and tandem mass spectrometry, and protein bioinformatics. This is a lab/lecture course where students will study background and theory and practice some of these techniques in the lab. 



Course Code
BCBT 469  Credits 1-12 
Title Internship 
Course Outline Course Outline 
Description This course is the required capstone experience for the Biochemistry and Biotechnology Certificate Program. An internship or work experience is required to complete the Biochemistry and Biotechnology Certificate. The experience can be a paid or volunteer experience. The experience needs to be approved by a faculty advisor in the Biochemistry and Biotechnology Certificate Program. Following the internship or work experience the student will be required to write a paper pertaining to the experience. Student must be in junior standing in a bioscience or chemistry major.